Hydrochlorothiazide is a diuretic, also called a water pill, that may be used to reduce edema (fluid retention) caused by the following conditions.
Congestive heart failure, which is a condition where the heart is not pumping as well as it should
Liver disease, such as cirrhosis, which can lead to a buildup of fluid in the abdomen (ascites)
Kidney disease, including protein in the urine (nephrotic syndrome)
Fluid caused by the use of hormones, such as estrogen or other steroids